Drug of choice for status epilepticus








Status Epilepticus Tx Often Falls Short - MedPage Today

8/19/2014
01:25 | Author: Molly Young

Status epilepticus protocol
Status Epilepticus Tx Often Falls Short - MedPage Today

WASHINGTON -- Treatment of status epilepticus in critically ill the field needs more research on second- and third-line drug choices and on.

The last step is continuous infusion of anesthetic drugs such as midazolam, phenobarbital, or propofol. If the episode continues, the next step is IV doses of a nonbenzodiazepine anti-epileptic drug (AED) such as phenytoin, levetiracetam, or valproate. Step 3 is a second nonbenzodiazepine drug including lacosamide, topiramate, pregabalin, carbamazepine, or oxcarbazepine. The standard treatment algorithm for status epilepticus begins with intravenous bolus doses of a benzodiazepine such as lorazepam or diazepam.

In the hospital, Loddenkemper added, personnel could receive more training in the importance of status epilepticus and its rapid treatment.

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Chapt 15Drugs for Seizures flashcards Quizlet

6/18/2014
01:10 | Author: Jeremy Rodriguez

Status epilepticus first line treatment
Chapt 15Drugs for Seizures flashcards Quizlet

What drug is given to terminate status epilepticus? Amobarbial (Amytal).    What is the drug of choice for neonatal seizures? phenobarbital.   .

Vitamin D and folate deficiency.

mainly phenobarbital and primidone for all seizures except partial seizures.

Seizures that travel through the entire brain.

Sedative-hypnotic drug; anticonvulsant drug, barbiturate drowsiness, lethargy, delirium.

generalized tonic-clonic seizure (grand mal seizure_ myoclonic seizure.

Very short lasting seizure during which the patient may stumble and fall for no apparant reason.

suppression of the influx fo sodium into neurons GABA restlessness and agitation.

inherited epilepsies, CNS infections,neurologic degenerative disorders.

Symptom of epilepsy characterized by abnormal neuronal discharges by the brain.

petit mal- lasting a few seconds, seen most often in children, stares into space, no response to verbal commands, may have fluttering eyelids or jerking, misdiagnosed in children as ADD or daydreaming.

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Grand Mal- Aura (preceeding), intense muscle contraction (tonic phase) followed by alternating contraction and relaxation of muscles (clonic phase), crying at beginning as air leaves lungs, loss of bowel/bladder control, shallow breating with periods of apnea, usually lasting 1-2 minutes, disorientation and deep sleep after seizure (postictal state).

anticonvulsant Na channel blocker Ataxia, gingival hyperplasia.

They are teratogenic, they interfere with oral contraceptives, they produce folic acid deficiency Chronic repsiratory dysfuncion Romazicon.

drop attacks, falling or stumbling for no reason, lasting a few seconds.

immediay reporting unusual bleeding or bruises to the health care provider Dilantin, Depakene, Tegretol acute, chronic.

Disorder of the CNS characterized by seizures and/or convulsions.

may cause folate deficiency, a condition correlated with fetal neural tube defects.

Uncontrolled muscle contraction or spasm that occurs in the face, torso, arms or legs Pregnancy-induced hypertensive disorder.

suppressing repetitive and abnorman neuronal firing.

Seizure that starts on one side of the brain and travels a short distance before stopping.

Seizure characterized by intense jerking motions and loss of consciousness.

infection, trauma, metabolic disorder, vasular disease, neoplastic disorders barrier method folate sleep, strobe, flickering.

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no memory of seizure.

Anticonvulsant, Succinimide drug, Ca blocker Dizziness, drowsiness, gastric distress, nausea.

Neurotransmitter in the CNS.

congenital abnormalities of the CNS, perinatal brain injury, metabolic imbablance related to seizure activity in neonates, infants and toddler.

phenobarbital.

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Status epilepticus - SlideShare

4/17/2014
03:15 | Author: Molly Young

Status epilepticus protocol
Status epilepticus - SlideShare

A comparison of survival by duration in status epilepticus shows a marked. followed by phenytoin (or fosphenytoin) are the drugs of choice.

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Anticonvulsants Used to Stop Ongoing Seizure Activity Systemic

2/16/2014
05:40 | Author: Jeremy Rodriguez

Status epilepticus protocol
Anticonvulsants Used to Stop Ongoing Seizure Activity Systemic

Because diazepam has a rapid onset of action that prevents the spread of the seizure, it is usually the drug of choice for controlling status epilepticus and.

Because diazepam has a rapid onset of action that prevents the spread of the seizure, it is usually the drug of choice for controlling status epilepticus and stopping seizures in both small and large animals. In status epilepticus, treatment is essential to prevent death from hyperthermia, acidosis, hypoperfusion, and hypoxia.

In some cases, inhalation anesthesia is necessary to control or stop seizure activity. This requires constant monitoring.

Ocular compression (application of digital pressure to one or both eyes) may be beneficial via stimulation of the vagus nerve.

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Emergency management of the paediatric patient with generalized

10/25/2014
03:15 | Author: Molly Young

Status epilepticus first line treatment
Emergency management of the paediatric patient with generalized

Anticonvulsant drug therapies for convulsive status epilepticus. Benzodiazepines are the first-line drugs of choice in the treatment of CSE.

Common etiologies are listed in Table 1. Mortality has been reported to be between 2.7% and 8%, with an overall morbidity (mainly newly diagnosed neurological disorders) of between 10% and 20%. Acute. The annual incidence of CSE in children is reported as 10 to 73 episodes/100,000 children and is highest (135/100,000 to 156/100,000 children) in children younger than two years of age.

First choice in neonates, or if on phenytoin maintenance Paraldehyde‡ (PR).

Note that evidence for the safety and efficacy of IO phenytoin or phenobarbital is scant.

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