Epilepsy drugs








Antiepileptic drugs indications other than epilepsy

10/22/2014
12:40 | Author: Jeremy Rodriguez

Epilepsy drugs
Antiepileptic drugs indications other than epilepsy

Antiepileptic drugs: indications other than epilepsy. Spina E, Perugi G. Antiepileptic drugs (AEDs) are increasingly used for the treatment of several non-epileptic.

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AEDs are also used to treat psychiatric conditions, in particular bipolar disorder. Lamotrigine, oxcarbazepine, gabapentin and topiramate appear to be promising in the treatment of refractory bipolar disorder, as a monotherapy as well as in combination with traditional mood stabilizers.

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Safety Alerts for Human Medical Products Antiepileptic Drugs

12/21/2014
10:20 | Author: Jeremy Rodriguez

Epilepsy drugs
Safety Alerts for Human Medical Products Antiepileptic Drugs

[UPDATE 05/05/2009] FDA notified healthcare professionals that it approved updated labeling for antiepileptic drugs used to treat epilepsy.

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[September 2009 - Dear Healthcare Professional Letter - Klonopin (clonazepam) - Roche]

Dear Healthcare Professional Letter for Klonopin (clonazepam) added below.

[December 16, 2008 - Drug Information Page - FDA] [January 31, 2008 - Healthcare Professional Information Sheet - FDA]

Based on the outcome of this review, FDA is requiring that all manufacturers of drugs in this class include a Warning in their labeling and develop a Medication Guide to be provided to patients prescribed these drugs to inform them of the risks of suicidal thoughts or action.

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Use of antiepileptic drugs during pregnancy and risk of spontaneous

10/20/2014
08:20 | Author: Jeremy Rodriguez

Epilepsy drugs
Use of antiepileptic drugs during pregnancy and risk of spontaneous

Objective To determine whether use of antiepileptic drugs during pregnancy may increase the risk of spontaneous abortion or stillbirth.

We identified 4700 (0.5%) pregnancies exposed to antiepileptic drugs. Table 1 ⇓ shows the characteristics of the total study population. Our study included a total of 983 305 pregnancies of which 109 800 resulted in a spontaneous abortion (11%), 3222 in stillbirths (0.3%), and 175 694 in induced abortions (18%). Furthermore, induced abortions were more common among women who used than did not use antiepileptics. Women who used antiepileptics also were more likely to have a history of a psychiatric disorder (including severe psychiatric disorders), substance misuse, and use of antipsychotics and antidepressants.

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