Ginger University of Maryland Medical Center






Getgetnet.bizGinger medicinal uses side effects


5/21/2014
02:27 | Author: Molly Young

Medication interactions and side effects
Ginger University of Maryland Medical Center

Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation, and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice. J Nutr. Fuhrman B, Rosenblat M, Hayek T, Coleman R, Aviram M. 2000;130(5):.

2003;307(3):. Ginger reduces hyperglycemia-evoked gastric dysrhythmias in healthy humans: possible role of endogenous prostaglandins. Gonlachanvit S, Chen YH, Hasler WL, et al. J Pharmacol Exp Ther.

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Ginger is native to Asia where it has been used as a cooking spice for at least 4,400 years.

Portnoi G, Chng LA, Karimi-Tabesh L, et al. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. 2003;189(5):. Am J Obstet Gynecol.

Pongrojpaw D, Somprasit C, Chanthasenanont A. A randomized comparison of ginger and dimenhydrinate in the treatment of nausea and vomiting in pregnancy. J Med Assoc Thai. 2007 Sep;90(9):1703-9.

Nausea and vomiting after surgery.

In one small study, people were given either fresh root or powdered ginger, scopolamine, a medication commonly prescribed for motion sickness, or placebo. Those who took scopolamine had fewer symptoms than those who took ginger. Conventional prescription and over-the-counter medicines for nausea may also have side effects, such as dry mouth and drowsiness, that ginger does not. However, other studies found that ginger does not work as well as medications for motion sickness.

Several studies -- but not all -- suggest that ginger may work better than placebo in reducing some symptoms of motion sickness. A study with healthy volunteers found the same thing. Ginger did not reduce their nausea, however. In one trial of 80 new sailors who were prone to motion sickness, those who took powdered ginger had less vomiting and cold sweating compared to those who took placebo.

It is also used to treat mild stomach upset, to reduce pain of osteoarthritis, and may even be used in heart disease. Today, health care professionals may recommend ginger to help prevent or treat nausea and vomiting from motion sickness, pregnancy, and cancer chemotherapy. Motion Sickness.

Pregnant or breastfeeding women, people with heart conditions and people with diabetes should not take ginger without asking their doctors.

1991 Jan 4;38(1):19-24. Eur J Obstet Gynecol Reprod Biol. Ginger treatment of hyperemesis gravidarum. Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U.

Herbs, however, can trigger side effects and interact with other herbs, supplements, or medications. The use of herbs is a time-honored approach to strengthening the body and treating disease. For these reasons, herbs should be taken with care, under the supervision of a health care provider qualified in the field of botanical medicine.

Ginger: an overview. Am Fam Physician. White B. 2007;75(11):1689-91.

Larkin M. Lancet. Surgery patients at risk for herb-anaesthesia interactions. 1999; :1362.

Wang CC, Chen LG, Lee LT, et al. 2003;17(6):641-645. Effects of 6-gingerol, an antioxidant from ginger, on inducing apoptosis in human leukemic HL-60 cells. In Vivo.

Langner E, Greifenberg S, Gruenwald J. Ginger: history and use. 1998;15(1):25-44. Adv Ther.

Pediatric. You can also buy fresh ginger root and make a tea. Ginger products are made from fresh or dried ginger root, or from steam distillation of the oil in the root. Ginger is a common cooking spice and can be found in a variety of foods and drinks, including ginger bread, ginger snaps, ginger sticks, and ginger ale. You can find ginger extracts, tinctures, capsules, and oils.

Eberhart LH, Mayer R, Betz O, et al. Anesth Analg. Ginger does not prevent postoperative nausea and vomiting after laparoscopic surgery. 2003;96(4):995-8, table.

Blood-thinning medications -- Ginger may increase the risk of bleeding. Talk to your doctor before taking ginger if you take blood-thinners such as warfarin (Coumadin), clopidogrel (Plavix), or aspirin.

Am Fam Physician. Review. 2008 Jan 15;77(2):177-84. Gregory PJ, Sperry M, Wilson AF. Dietary supplements for osteoarthritis.

African ginger; Black ginger; Jamaican ginger; Zingiber officinale.

Vaes LP, Chyka PA. 2000;34(12):. Ann Pharmacother. Interactions of warfarin with garlic, ginger, ginkgo, or ginseng: nature of the evidence.

2003; :259-265. Nurtjahja-Tjendraputra E, Ammit AJ, Roufogalis BD, et al. Effective anti-plaet and COX-1 enzyme inhibitors from pungent constituents of ginger. Thromb Res.

Don’t give ginger to children under 2.

Make sure to l your doctor if you are taking ginger before having surgery or being placed under anesthesia for any reason. People with gallstones should ask their doctor before taking ginger.

If you take any of the following medications, you should not use ginger without first talking to your health care provider. Ginger may interact with prescription and nonprescription medications.

Osteoarthritis Cartilage. The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Wigler I, Grotto I, Caspi D, et al. 2003;11(11):783-789.

2000;8:9-12. A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis. Osteoarthritis Cartilage. Bliddal H, Rosetzsky A, Schlichting P, et al.

Ginger -- the "root," or actually the rhizome, of the plant Zingiber officinale -- has been a popular spice and herbal medicine for thousands of years. It has a long history of being used as medicine in Asian, Indian, and Arabic herbal traditions. In China, for example, ginger has been used to help digestion and treat stomach upset, diarrhea, and nausea for more than 2,000 years. Ginger has also been used to help treat arthritis, colic, diarrhea, and heart conditions.

Pregnant women should not take more than 1g per day. In general, don’t take more than 4g of ginger per day, including food sources.

1990;45(8):669-71. Bone ME, Wilkinson DJ, Young JR, McNeil J, Charlton S. Ginger root -- a new antiemetic. Anaesthesia. The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery.

2001;97(4):577-582. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol. Vutyavanich T, Kraisarin T, Ruangsri R.

Do not take ginger if you have a bleeding disorder or if you are taking blood-thinning medications, including aspirin.

Sripramote M, Lekhyananda N. 2003;86(9):846-853. J Med Assoc Thai. A randomized comparison of ginger and vitamin B6 in the treatment of nausea and vomiting of pregnancy.

1988;105:45-49. Ginger root against seasickness: a controlled trial on the open sea. Grontved A, Brask T, Kambskard J, Hentzer E. Acta Otolaryngol.

In a small study of 30 pregnant women with severe vomiting, those who took 1 gram of ginger every day for 4 days reported more relief from vomiting than those who took placebo. Chemotherapy nausea. In a larger study of 70 pregnant women with nausea and vomiting, those who got a similar dose of ginger felt less nauseous and did not vomit as much as those who got placebo. Pregnant women should ask their doctor before taking ginger, and not take more than 1g per day.

Altman RD, Marcussen KC. Arthritis Rheum. Effects of a ginger extract on knee pain in patients with osteoarthritis. 2001;44(11):.

A few studies suggest that ginger reduces the severity and duration of nausea -- but not vomiting -- during chemotherapy. However, one of the studies used ginger combined with another anti-nausea drug, so it's hard to say whether ginger had any effect. More studies are needed.

2003;23(5A):. Mahady GB, Pendland SL, Yun GS, et al. Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+ strains of Helicobacter pylori. Anticancer Res.

This page was last updated: July 31, 2013.

2008;46(2):409-20. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem Toxicol. Ali BH, Blunden G, Tanira MO, Nemmar A.

Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. B J Anaesth. Ernst E, Pittler MH. 2000;84(3):367-371.

You may be able to avoid some of the mild stomach side effects, such as belching, heartburn, or stomach upset, by taking ginger supplements in capsules or taking ginger with meals. In high doses it may cause mild heartburn, diarrhea, and irritation of the mouth. It's rare to have side effects from ginger.

Ask your doctor to help you find the right dose. Adult. Children over 2 make take ginger to treat nausea, stomach cramping, and headaches.

It may take several weeks for ginger to work. Other uses. Traditional medicine has used ginger for centuries to reduce inflammation. But another study found that ginger was no better than ibuprofen (Motrin, Advil) or placebo in reducing symptoms of OA. And there is some evidence that ginger may help reduce pain from osteoarthritis (OA). In a study of 261 people with OA of the knee, those who took a ginger extract twice daily had less pain and needed fewer pain-killing medications than those who received placebo.

The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. Thomson M, Al Qattan KK, Al Sawan SM, et al. Prostaglandins Leukot Essent Fatty Acids. 2002;67(6):475-478.

High blood pressure medications -- Ginger may lower blood pressure, raising the risk of low blood pressure or irregular heartbeat.

2006;194(1):95-9. Chaiyakunapruk N. Am J Obstet Gynecol. The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis.

Researchers think the active components of the ginger root are volatile oils and pungent phenol compounds (such as gingerols and shogaols).

It has been used to help treat the common cold, flu-like symptoms, headaches, and painful menstrual periods.

J Med Assoc Thai. 2006;89(12):2003-9. Effectiveness of ginger for prevention of nausea and vomiting after gynecological laparoscopy. Apariman S, Ratchanon S, Wiriyasirivej B.

Ginger is a knotted, thick, beige underground stem, called a rhizome. The stem sticks up about 12 inches above ground with long, narrow, ribbed, green leaves, and white or yellowish-green flowers.

Phillips S, Ruggier R, Hutchinson SE. 1993;48(8):715-717. Zingiber officinale (ginger) -- an antiemetic for day case surgery. Anaesthesia.

In one of these studies, women who took ginger also needed fewer medications for nausea after surgery. More research is needed. In fact, one study found that ginger may actually increase vomiting following surgery. But other studies have found that ginger didn't help reduce nausea. Research is mixed as to whether ginger can help reduce nausea and vomiting following surgery. Osteoarthritis. Two studies found that 1g of ginger root before surgery reduced nausea as well as a leading medication.

Human studies suggest that 1g daily of ginger may reduce nausea and vomiting in pregnant women when used for short periods (no longer than 4 days). Several studies have found that ginger is better than placebo in relieving morning sickness.

2003;43(2):139-144. Effect of a ginger extract on pregnancy-induced nausea: a randomised controlled trial. Willetts KE, Ekangaki A, Eden JA. Aust N Z J Obstet Gynaecol.

Pregnancy-Related Nausea and Vomiting.

2000;57(13):. Am J Health Syst Pharm. Potential interactions between alternative therapies and warfarin. Heck AM, DeWitt BA, Lukes AL.

That can raise the risk of developing hypoglycemia or low blood sugar. Diabetes medications -- Ginger may lower blood sugar.

Bordia A, Verma SK, Srivastava KC. Prostaglandins Leukot Essent Fatty Acids. Effect of ginger ( Zingiber officinale Rosc. 1997;56(5):379-384. ) on blood lipids, blood sugar, and plaet aggregation ion patients with coronary heart disease. ) and fenugreek ( Trigonella foenumgraecum L.

Lee SH, Cekanova M, Baek SJ. 2008;47(3):197-208. Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Mol Carcinog.


Ginger medicinal uses side effects