Intractable epilepsy








Intractable Epilepsy - University of Rochester Medical Center

12/13/2014
04:14 | Author: Chloe Allen

Intractable epilepsy
Intractable Epilepsy - University of Rochester Medical Center

Intractable epilepsy is a seizure disorder in which a patient's seizures fail to come under control with treatment. These seizures are sometimes also called.

Intractable epilepsy is a seizure disorder in which a patient’s seizures fail to come under control with treatment. These seizures are sometimes also called “uncontrolled” or “refractory.”.

Intractable epilepsy does not always remain intractable. First, one of the treatments listed below may prove effective. Second, individuals may be able to modify precipitating factors or their lifestyle to help to control the seizures. But even in the absence of specific therapies or life changes, there is hope for improvement for spontaneous regression which is reported to occur in about 5% of patients with this condition.

People who are not seizure-free need to be careful about possible accidents during a seizure.

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Definition of intractable epilepsy

10/12/2014
02:32 | Author: Chloe Allen

Intractable epilepsy
Definition of intractable epilepsy

Defining intractable epilepsy is essential not only to identify up to 40% of patients refractory to pharmacological management, but also to facilitate selection and.

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National Center for Biotechnology Information, U.S. National Library of Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA.

Multiple factors including number of antiepileptic drug (AED) failures, seizure frequency and duration of unresponsiveness, etiology, and epilepsy syndromes are considered in formulating the definition of pharmaco-resistant epilepsy. Most definitions used in the literature agree on the number of AED failures, which seem to be 2 or 3, however, the seizure frequency and time factor are varied. However, with emergence of new data and novel treatments the criteria for intractability may change. The International League Against Epilepsy proposed a definition of drug-resistant epilepsy as a failure of adequate trials of 2 tolerated and appropriay chosen and used AED schedules. Defining intractable epilepsy is essential not only to identify up to 40% of patients refractory to pharmacological management, but also to facilitate selection and comparison of such patients for research purposes. The ideal definition still eludes us. This for now, could provide an operational definition for clinical and research settings.

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Medical Intractability in Epilepsy Neurosurgery University of

8/11/2014
12:02 | Author: Jeremy Rodriguez

Intractable epilepsy
Medical Intractability in Epilepsy Neurosurgery University of

Medical management with AEDs remains the treatment of choice for epilepsy in adults and children. Medically intractable epilepsy has been defined as.

Epileptic foci secondary to lateral neocortical and extratemporal anomalies in children are frequently due to architectural abnormalities, such as cortical dysplasia, migrational defects, and other congenital developmental abnormalities. (888) (412). In the future, further improvements in neuroimaging may replace the need for invasive evaluation in this group of patients. As a result, many of these patients require chronic invasive monitoring to further define the seizure focus, particularly the relationship to normal, eloquent areas of cortex.

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Refractory Epilepsy Epilepsy Foundation

6/10/2014
02:16 | Author: Allison King

Intractable epilepsy
Refractory Epilepsy Epilepsy Foundation

A number of different terms may be used to describe these including: “uncontrolled,” “intractable,” “refractory,” or “drug resistant.” How often does this happen?.

Another reason for uncontrolled seizures is poor or less than optimal treatment. In other words, the ‘wrong key’ is being used to unlock the door! Common reasons for suboptimal treatment are listed below.

People have been referred to epilepsy centers for brain surgery, when their underlying condition was not epilepsy, but one of the imitators. Experienced clinicians are skilled at using a combination of the medical history, the physical exam and certain laboratory tests to determine whether sudden episodes with alteration in sensation, strength, behavior or awareness are seizures or one of the imitators.

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Medically Intractable Epilepsy - Neuromodulation and Functional

4/9/2014
04:10 | Author: Jeremy Rodriguez

Medicine is stopped
Medically Intractable Epilepsy - Neuromodulation and Functional

We believe that anyone with epilepsy who is still having seizures despite trying several medications at reasonable doses is intractable.

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