Cognitive side effects of antiepileptic drugs in children
Neurology. 2004 Mar 23;62(6):872-7. Cognitive side effects of antiepileptic drugs in children. Loring DW(1), Meador KJ. Author information: (1)Department of.
Unfortunay, there have been few studies examining the cognitive effects of AEDs in this population and no adequate studies of newer AEDs. Although it will be necessary to overcome many programmatic and procedural hurdles, well-designed randomized prospective studies that are of adequate length to determine how AEDs ultimay relate to school performance and social adjustment are needed to firmly establish the cognitive and behavioral effects of AEDs in children. Because of various limitations in the designs of these studies, however, many of the studies report inconclusive findings. Cognitive impairment associated with antiepileptic drug (AED) therapy in children is an important concern given the potential negative effects of treatment on school learning and performance. This article will discuss the effects of the traditional and newer AEDs on neuropsychological function in children.
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